Figure 4. The MDA concentrations (A), SOD activity (B), CAT activity (C), total thiol contents (D) association between losartan and oxidant/anti-oxidant markers in tissue (E). Data are shown as mean ± SEM (n = 6 per group). ** P < 0.01 and *** P < 0.001 compared with control group, ^## P < 0.01 and ^### P < 0.001 compared with 5-FU group.