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. 2020 May 26;63(1):e60. doi: 10.1192/j.eurpsy.2020.55

Table 1.

Characteristics and findings of reviewed studies.

References Country N Cohort Age (M ± SD) Gender Follow-up ED diagnosis ED diagnostic threshold Findings Quality
Ackard et al. [40] United States 2,516 Project EAT-II; 31 schools 20.4 ± 0.8 at follow-up 45% male 5 years Self-report questions re: ED criteria (DSM-IV) Full threshold ED cases 2.2% males and females with body image disturbance developed BED or BN. 0.9% of males and 3.7% of females with binge eating or compensatory behaviors developed BED, or BED and BN, respectively. Poor
Allen et al. [41] Australia 1,597 Raine study; birth cohort 14.1 ± 0.1 at follow-up 55% male 14 years Adapted child EDE and EDEQ (DSM-IV) Full, partial, and “at risk” ED cases A restricted diet predicted later ED cases. Good
Beato-Fernandez et al. [42] Spain 1,076 22 schools 12–13 at baseline 46% male 2 years EAT-40 (DSM-III-R/IV) Full (AN, BN) and EDNOS cases Body dissatisfaction predicted later ED diagnosis. Those who developed an ED had more suicidal and self-harm tendencies, worse depressive symptoms, and body dissatisfaction at baseline. Poor
Herle et al. [43] United Kingdom 4,760 ALSPAC 1.3 at baseline 52% male 8.7 years Data from YRBSSQ and DEBQ (DSM-5) Full threshold ED cases Childhood overeating, persistent undereating, and persistent fussy eating were predictive of adolescent binge eating disorder, anorexia nervosa (girls only), and anorexia nervosa (whole sample), respectively. Good
Johnson et al. [44] United States 726 Families from two NY counties 13.8 ± 2.6 at baseline 49% male 10 years DISC-I (DSM-III-R) Full Threshold ED cases and ED behaviors Depressive and anxiety disorders were predictive of EDs. Disruptive and substance use disorders were not predictive of EDs. Good
Killen et al. [45] United States 887 4 schools 12.4 ± 0.7 at baseline All female 3 years Self-report questions (diagnostic tool not reported) Full and partial ED cases Elevated weight concerns associated with onset of partial EDs. Earlier drive for thinness, body dissatisfaction, perfectionism, and restraint most characteristic of those who later develop partial EDs Poor
Killen et al. [46] United States 825 4 schools 14.9 at baseline All female 4 years Interview and adapted EDE (DSM-III-R) Full and partial ED cases Elevated weight concerns associated with onset of partial EDs. Earlier drive for thinness, bulimia, body dissatisfaction, ineffectiveness, interoceptive awareness, temperament (distress, fear), dieting, restraint, and alcohol use most characteristic of those who later develop partial EDs. Good
Kotler et al. [47] United States 976 Families from two NY counties 6.1 at baseline 50% male 17 years DISC (DSM-III-R/IV) Full threshold ED cases and ED behaviors Eating conflicts, struggles with food and unpleasant meals predicted AN. Good
Liechty and Lee [48] United States 14,322 Add Health; 80 high schools 15.9 ± 1.8 at baseline 49% male 7 years Self-report (ever told have an ED? yes/no) Implied full threshold ED cases Depression, body image dissatisfaction (males only), and extreme weight loss behaviors (females only) was associated with unspecified ED diagnosis. Good
Marchi and Cohen [49] United States 659 9 schools ~6 years at baseline 51% male 10 years DISC (DSM-III-R) Full threshold ED cases Risks in early childhood for subsequent symptoms of anorexia nervosa include picky eating and digestive problems.
Early symptoms of AN/BN predictive of later diagnosis and pica predictive of BN.
Good
Neumark-Sztainer et al. [50] United States 2,516 Project EAT-II; 31 schools 12.8/15.8 ± 0.8 at baseline 45% male 5 years Self-report (ever told have an ED? yes/no) Implied full threshold ED cases and ED behaviors In females, dieting significantly associated with later EDs. Poor
Nicholls and Viner [51] United Kingdom 16,567 BCS70; birth cohort From birth 56% male 30 years Self-report (ever told have an ED? yes/no) Implied full threshold ED cases Infant feeding problems, under eating, and increased exercise (at 10 years) associated with later AN. Poor
Nicholls et al. [52] United Kingdom 16,567 BSC70; birth cohort From birth 49% male 30 years Self-report (ever told have an ED? yes/no) Implied full threshold ED cases Eating, sleep problems, and overeating (5 years) associated with later BN/BED. Poor
Patton et al. [53] Australia 1,947 45 schools 14.5 ± 0.5 at baseline 47% male 3 years BET (DSM-IV) Full and partial syndrome ED cases In females, severe and moderate dieting increased risk of future ED. Psychiatric morbidity (independent of dieting) predicted onset of EDs. Poor
Penas-Lledo et al. [54] Sweden 615 TChAD; Twin study 16–17 years at baseline All female 3 years Self-report (ever had BN or AN? Yes/no) Implied full threshold ED cases Drive for thinness predicted later BN. Interaction between drive for thinness and anxious/depressed mood predicted risk of both BN and AN. Poor
Ranta et al. [55] Finland 3,278 Finnish Adolescent Mental Health Cohort Study 15.5 ± 0.4 at baseline 51% male 2 years Self-report questions re: ED criteria (DSM-IV-TR) Implied full threshold ED cases Depression predicted AN, while social phobia and depression both predicted BN. However, controlling for initial comorbidity, Eds, and socioeconomic factors removed this effect. Poor
Schaumberg et al. [56] United Kingdom 7,767 ALSPAC 10 years Not reported 6 years Data from YRBSSQ & DEBQ (DSM-5) Full threshold ED cases Physical anxiety symptoms predicted BN, while worries (e.g., about the future) predicted AN. Fair
Stice et al. [57] United States 496 8 schools 13.5 ± 0.7 at baseline All female 2 years EDE (DSM-IV) Full and partial threshold ED cases Depressive symptoms (but not substance abuse) predicted onset of subthreshold BN. Good
Stice et al. [58] United States 496 8 schools 15.4 ± 0.7 at baseline All female 5 years EDDI (DSM-IV) Full and partial threshold ED cases Fasting (not eating for 24 hours) for weight control more predictive of future sub/full BN than dietary restraint. Good
Stice et al. [59] United States 496 8 schools 13.5 ± 0.7 at baseline All female 8 years EDDI (DSM-IV) Full and partial threshold ED cases Body dissatisfaction predictive of ED onset. Those with high or low body dissatisfaction and elevated depressive or dieting associated with increased ED onset respectively. Good
Stice and Van Ryzin [60] United States 496 8 schools 13.5 ± 0.7 at baseline All female 8 years EDDI (DSM-IV) Full and partial threshold ED cases Growth curve models showed perceived pressure to be thin and/or thin-ideal internalization, before showing onset of disorder-predictive levels of body dissatisfaction, before showing onset of disorder-predictive levels of dieting and/or negative affect, before showing onset of the ED. Good
Wilkinson et al. [61] United Kingdom 945 Roots study 14 at baseline 47% male 3 years K-SADS-PL (DSM-IV) Full threshold ED cases Recurrent nonsuicidal self-injury predicted onset of EDs. Good

Abbreviations: ALSPAC, UK Avon Longitudinal Study of Parents and Children; AN: anorexia nervosa; BCS70, 1970 British Cohort Study; BED: binge eating disorder; BET, Branched Eating Disorders Test; BN: bulimia nervosa; DEBQ, Dutch Eating Behavior Questionnaire; DISC-II, Diagnostic Interview Schedule for Children, Version 2; DSM (-III-R/-IV/-5), Diagnostic and Statistical Manual of Mental Disorders, Third (Revised)/Fourth/Fifth Edition; EAT-40: Eating Attitudes Test; ED, eating disorder; EDDI: Eating Disorder Diagnostic Interview; EDE, Eating Disorder Examination; EDE-Q, Eating Disorder Examination Questionnaire; EDI: Eating Disorder Inventory; EDNOS, Eating Disorder Not Otherwise Specified; KSADS-PL, Kiddie Schedule for Affective Disorders and Schizophrenia, Present and Lifetime version; Project EAT-II, Eating Among Teens; TChAD, Twin study of Child and Adolescent Development; YRBSSQ, Youth Risk Behavior Surveillance System Questionnaire.