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ESR1 regulation dynamics represented by topic weights. (a) Pairwise KL divergence between the topic weights of ESR1 in all time points. (b) Time-course change of the topics with the highest weights across the time points. (c) and (d) Expression of the genes gained in 10 (c) and 40 min (d), as compared to 0 min, that are among the top-ranked genes of Topic 4
