Table 3.

Results of the logistic regression analyses for the ADHD PRS

ADHD PRS threshold	B	Wald p uncorrected	Bonferroni corr. Wald p	OR	Nagelkerke R2 PRS
ADHD/ASD sample (N = 688)
0.01	0.243	1.80×10−05	1.30×10−03	1.275	0.013
0.05	0.274	2.00×10−06	1.44×10−04	1.316	0.016
0.1	0.278	2.00×10−06	1.44×10−04	1.321	0.017
0.2	0.287	7.91×10−07	5.70×10−05	1.333	0.018
0.3	0.304	1.68×10−07	1.21×10−05	1.355	0.020
0.4	0.297	2.96×10−07	2.13×10−05	1.346	0.019
0.5	0.297	2.88×10−07	2.07×10−05	1.346	0.019
1	0.297	2.71×10−07	1.95×10−05	1.346	0.019
ADHD sample (N = 280)
0.01	0.337	5.00×10−06	3.60×10−04	1.401	0.024
0.05	0.356	2.00×10−06	1.44×10−04	1.428	0.026
0.1	0.401	2.52×10−07	1.82×10−05	1.493	0.031
0.2	0.454	9.68×10−09	6.97×10−07	1.574	0.039
0.3	0.472	1.93×10−09	1.39×10−07	1.603	0.043
0.4	0.482	7.98×10−10	5.75×10−08	1.620	0.045
0.5	0.479	9.87×10−10	7.11×10−08	1.614	0.044
1	0.485	6.57×10−10	4.73×10−08	1.625	0.045
ASD sample (N = 295)
0.01	0.176	1.45×10−02	1	1.192	0.007
0.05	0.201	7.33×10−03	5.28 × 10−01	1.222	0.008
0.1	0.169	2.35×10−02	1	1.184	0.006
0.2	0.132	7.82 × 10−02	1	1.141	0.003
0.3	0.135	6.83 × 10−02	1	1.144	0.004
0.4	0.119	1.05 × 10−01	1	1.127	0.003
0.5	0.129	7.83 × 10−02	1	1.138	0.003
1	0.130	7.68 × 10−02	1	1.139	0.004

All models have eight PCs and sex as covariate (baseline model). Bonferroni P-value corrected for 72 tests. Sig. P-values are shown in bold. Results of the logistic regression analyses for the ASD and SCZ PRS are presented in the Supplementary Tables 3 and 4