Table 9.

Effect of 50–400 mg/kg/day of CVE on serum LDH and cardiac troponin I in DOX-intoxicated rats.

Treatment groups	LDH (U/L)	Troponin I (ng/ml)
I	4204 ± 637.1a+	21.18 ± 7.72c+
II	3734 ± 251.5	3.29 ± 2.41f–
III	2781 ± 657.5d–	7.93 ± 7.03d–
IV	2939 ± 184.1d–	10.63 ± 6.7d–
V	2530 ± 189.2d–	2.96 ± 1.71f–
VI	2214 ± 340.1d–	3.53 ± 1.84f–
VII	2907 ± 204.4d–	3.46 ± 1.71f–
VIII	3331 ± 227.5	4.11 ± 2.59

^{a+, c+}Significant increases at p < 0.05 and p < 0.0001, respectively, when compared to the untreated negative (normal) control values. ^d−,f−Significant decreases at p < 0.05 and p < 0.0001, respectively, when compared to the untreated positive (doxorubicin treated only) control values, respectively.