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. 2020 Jan 9;43(7):zsz295. doi: 10.1093/sleep/zsz295

Table 6.

The performance of SVM model in subgroups including men, women, <65 y/o, and ≥65 y/o

AHI cutoff No. of ≥AHI cutoff AUROC F1 score Accuracy (%) Sensitivity (%) Specificity (%) PPV (%) NPV (%) LR+ LR−
Male ≥5 4,653 0.80 (0.77–0.83) 0.82 (0.80–0.83) 71.82 (69.59–74.04) 71.21 (69.04–73.37) 76.06 (73.04–79.08) 95.35 (94.67–96.04) 27.69 (25.55–29.84) 3.00 (2.59–3.42) 0.38 (0.34–0.42)
≥15 3,550 0.77 (0.77–0.78) 0.76 (0.70–0.81) 69.86 (65.74–73.98) 69.30 (59.97–78.63) 71.08 (63.99–78.16) 83.70 (81.83–85.58) 52.62 (48.17–57.07) 2.44 (2.07–2.82) 0.43 (0.35–0.51)
≥30 2,425 0.76 (0.74–0.78) 0.66 (0.59–0.73) 69.65 (67.17–72.13) 64.58 (52.25–76.91) 74.06 (67.47–80.64) 68.50 (66.53–70.48) 71.09 (66.21–75.98) 2.52 (2.29–2.74) 0.47 (0.36–0.59)
Female ≥5 1,106 0.78 (0.73–0.83) 0.79 (0.74–0.84) 72.76 (67.28–78.24) 77.75 (70.55–84.96) 62.64 (56.94–68.35) 80.79 (77.74–83.85) 58.64 (50.32–66.96) 2.11 (1.65–2.58) 0.36 (0.23–0.48)
≥15 661 0.79 (0.75–0.83) 0.67 (0.65–0.69) 67.92 (63.79–72.06) 81.84 (79.15–84.53) 58.64 (50.16–67.12) 57.13 (52.74–61.53) 82.87 (81.88–83.86) 2.02 (1.65–2.39) 0.31 (0.29–0.33)
≥30 366 0.79 (0.75–0.82) 0.52 (0.47–0.57) 68.17 (61.43–74.91) 77.04 (74.41–79.67) 65.64 (56.66–74.62) 39.47 (33.20–45.75) 90.91 (89.86–91.96) 2.33 (1.68–2.98) 0.35 (0.31–0.40)
<65 y/o ≥5 4,870 0.82 (0.79–0.85) 0.83 (0.80–0.85) 74.52 (71.62–77.41) 74.68 (71.42–77.93) 73.81 (69.80–77.82) 92.56 (91.41–93.71) 40.14 (36.42–43.86) 2.88 (2.46–3.31) 0.34 (0.29–0.40)
≥15 3,577 0.81 (0.80–0.82) 0.77 (0.74–0.81) 73.43 (71.47–75.39) 76.46 (68.81–84.10) 68.94 (62.42–75.46) 78.66 (76.51–80.82) 66.74 (62.27–71.22) 2.50 (2.15–2.85) 0.34 (0.27–0.41)
≥30 2,347 0.79 (0.78–0.81) 0.66 (0.62–0.70) 70.96 (69.22–72.70) 71.83 (62.05–81.61) 70.40 (63.93–76.87) 61.22 (58.19–64.25) 79.75 (75.68–83.82) 2.46 (2.13–2.79) 0.40 (0.29–0.50)
≥65 y/o ≥5 799 0.70 (0.64–0.76) 0.78 (0.76–0.79) 65.84 (63.68–68.00) 65.83 (63.37–68.30) 65.73 (52.01–79.45) 94.47 (92.42–96.52) 17.94 (14.85–21.04) 2.19 (0.88–3.50) 0.53 (0.43–0.63)
≥15 634 0.69 (0.67–0.72) 0.72 (0.66–0.79) 64.94 (59.99–69.88) 65.75 (54.68–76.82) 62.92 (50.00–75.84) 81.77 (77.98–85.57) 42.92 (39.06–46.79) 1.87 (1.33–2.40) 0.54 (0.46–0.63)
≥30 444 0.70 (0.68–0.72) 0.62 (0.54–0.69) 64.16 (61.20–67.12) 58.52 (45.19–71.85) 69.74 (60.90–78.58) 66.07 (63.15–68.99) 63.23 (58.75–67.71) 1.97 (1.71–2.23) 0.59 (0.47–0.71)
Male < 65 y/o ≥5 3,972 0.81 (0.78–0.84) 0.82 (0.80–0.84) 72.47 (70.56–74.37) 71.80 (69.64–73.97) 76.81 (72.96–80.67) 95.29 (94.52–96.06) 29.46 (27.70–31.22) 3.14 (2.63–3.65) 0.37 (0.33–0.40)
≥15 3,075 0.78 (0.77–0.79) 0.76 (0.72–0.81) 70.74 (67.41–74.07) 70.18 (61.74–78.62) 71.89 (64.65–79.14) 83.77 (81.54–86.01) 54.50 (50.56–58.44) 2.56 (2.08–3.05) 0.41 (0.34–0.48)
≥30 2,077 0.77 (0.75–0.79) 0.66 (0.61–0.72) 70.15 (68.40–71.91) 65.96 (54.65–77.26) 73.64 (67.30–79.97) 67.68 (65.67–69.69) 72.62 (68.15–77.10) 2.53 (2.29–2.78) 0.46 (0.35–0.56)
Male ≥ 65 y/o ≥5 591 0.66 (0.50–0.82) 0.77 (0.71–0.84) 64.99 (56.26–73.71) 65.65 (58.02–73.28) 57.09 (30.16–84.02) 94.53 (90.98–98.08) 13.31 (5.67–20.95) 1.82 (0.85–2.79) 0.81 (-0.07–1.70)
≥15 475 0.69 (0.64–0.75) 0.72 (0.59–0.85) 64.67 (52.79–76.55) 64.21 (46.97–81.45) 66.08 (57.94–74.23) 84.07 (81.07–87.07) 40.99 (30.06–51.92) 1.91 (1.45–2.37) 0.54 (0.31–0.76)
≥30 348 0.68 (0.65–0.72) 0.60 (0.51–0.70) 61.58 (57.45–65.71) 54.82 (40.88–68.77) 69.49 (61.48–77.50) 67.95 (66.43–69.47) 57.03 (52.80–61.27) 1.80 (1.68–1.92) 0.64 (0.52–0.77)
Female < 65 y/o ≥5 898 0.78 (0.72–0.84) 0.78 (0.74–0.83) 72.32 (67.63–77.01) 78.52 (72.21–84.82) 61.35 (55.96–66.73) 78.23 (75.33–81.13) 62.05 (54.74–69.35) 2.06 (1.67–2.45) 0.35 (0.24–0.46)
≥15 502 0.79 (0.76–0.83) 0.66 (0.62–0.70) 67.70 (62.00–73.39) 85.67 (81.39–89.94) 57.70 (48.59–66.82) 53.22 (48.26–58.19) 87.83 (84.22–91.43) 2.07 (1.68–2.45) 0.25 (0.17–0.33)
≥30 270 0.79 (0.76–0.83) 0.49 (0.43–0.55) 66.83 (59.86–73.80) 81.11 (76.69–85.54) 63.44 (55.04–71.83) 35.01 (28.68–41.34) 93.33 (91.53–95.14) 2.30 (1.61–2.99) 0.30 (0.21–0.39)
Female ≥ 65 y/o ≥5 208 0.71 (0.57–0.85) 0.78 (0.72–0.85) 68.88 (62.49–75.26) 68.31 (56.76–79.85) 71.07 (47.64–94.50) 93.19 (89.36–97.02) 29.79 (28.03–31.56) 3.14 (1.14–5.13) 0.44 (0.39–0.49)
≥15 159 0.68 (0.61–0.74) 0.66 (0.59–0.73) 60.30 (54.38–66.22) 60.32 (50.11–70.54) 60.39 (50.49–70.30) 73.41 (68.65–78.17) 46.04 (39.42–52.66) 1.56 (1.25–1.86) 0.66 (0.49–0.84)
≥30 96 0.70 (0.65–0.76) 0.59 (0.49–0.69) 66.88 (56.89–76.87) 60.47 (47.36–73.59) 70.95 (55.26–86.63) 58.64 (42.90–74.38) 73.92 (65.99–81.84) 2.66 (0.42–4.91) 0.57 (0.34–0.79)

The data were presented as mean (95% confidence interval).