Table 1.

Overall performance metrics of biomarker models

	LOOCV ACC	IV ACC	IV Sensitivity	IV Specificity	IV MCC
Compounds with and without 24-hour time-of-day patterns included
Logistic Regression (66)	100%	71%	47%	82%	0.30
Linear SVM (47)	97%	67%	47%	77%	0.23
Compounds with 24-hour time-of-day patterns excluded
Logistic Regression (65)	100%	74%	47%	85%	0.34
Linear SVM (65)	95%	74%	60%	79%	0.39

Numbers in parenthesis indicate total number of compounds in each biomarker model. ACC, accuracy.