Table 1.
Demographic variables before randomization
| Young n = 17 mean ± SD or median (IQR) | Old n = 18 mean ± SD or median (IQR) | P-value | |
|---|---|---|---|
| Age (yr) | 24.1 ± 2.9 | 63.9 ± 4.0 | <0.001 |
| Height (m) | 180 ± 7 | 175 ± 6 | 0.04 |
| BMI (kg/m2) | 25.0 (22.9–27.5)* | 29.5 (26.4–31.7)† | 0.002 |
| Albumin (g/dL) | 4.7 ± 0.2 | 4.2 ± 0.3 | <0.001 |
| LH (U/L) | 4.1 ± 2.0 | 4.9 ± 3.0 | 0.36 |
| FSH (U/L) | 3.4 ± 1.6 | 10.3 ± 2.98 | 0.002 |
| SHBG (nmol/L) | 28.6 ± 9.8 | 38.4 ± 10.1 | 0.006 |
| T (nmol/L) | 18.9 ± 4.7 | 14.9 ± 3.6 | 0.008 |
| Cortisol (nmol/L) | 202 ± 139 | 196 ± 122 | 0.9 |
| TSH (mU/L) | 2.3 ± 1.0 | 2.9 ± 1.3 | 0.14 |
| IGF-1 (ug/dL) | 195 ± 32 | 123 ± 37 | <0.001 |
†No young men and seven older men with BMI > 30 kg/m2.