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. 2020 Jun 5;12(6):516. doi: 10.3390/pharmaceutics12060516

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Fungal growth inhibition using free miconazole, as well as nano-vesicles at 1% and 2% miconazole. PBS was used as a control. (A) Significantly higher levels of inhibition were expressed using nano-vesicles as opposed to free miconazole, supporting the notion that nano-vesicles act as an inhibition enhancer. (B) Around 20% and 40% total fungal colonies were inhibited after 48 h with the miconazole nano-vesicles 1% and 2% treatment compared to PBS treated petri dishes, respectively. All data are presented as mean ± SE (n = 8). *p < 0.05 compared with the Actavis.