Figure 10.

The synergic effects and protein expression of DDX3 and Bcl-xL on combination treatment of curcumin and exemestane in HeLa, MDA-MB-231, and MCF-7 cell lines. (A) The various concentration of curcumin with or without 50 μM of exemestane was treated in the cell lines for 24 h. Control group (0 μM) was treated with same amount of DMSO. Then, the cell viability was measured by MTT assay. (B) The cell lines were treated with curcumin (10 and 20 μM) with or without exemestane (50 μM) for 24 h. The DDX3 and Bcl-xL expression levels were analyzed using Western blot. The β-actin protein was used as loading control. *** p < 0.001 vs. untreated group; ### p < 0.001 vs. only the same concentration of curcumin group.