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(a) The percentage distribution of crisaborole following the application of 2% ointment for 4 and 16 h; (b) the percentage distribution of crisaborole as a function of application time; and (c) the distribution of crisaborole in the skin and receptor compartment following application of ointment and 2% solution in ACN for 16 h (from Reference [17]). Average values ± sd. * denotes statistical differences (p < 0.05).
