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. 2020 May 28;12(6):491. doi: 10.3390/pharmaceutics12060491

Table 1.

Solvent properties and crisaborole solubility (average values ± sd).

Solvent Solubility Parameter (MPa1/2) Crisaborole Solubility (mg/mL)
Octanol 20.87 [25] 75.80 ± 1.70
Ethanol 26.52 [25] 40.6 ± 11.3
Propylene Glycol 30.22 [25] 12.20 ± 2.55
Oleic acid 17.39 [25] 3.44 ± 0.33
Isopropyl myristate 17.38 [26] 3.43 ± 1.68
Water 47.8 [25] 0.11 ± 0.01