Table 1.
Effect of A3 on oxidative enzymes.
| NO (μmoles/mg) | GST (µmoles CDNB Conjugate/min/mg of Protein) | GSH (µmoles/mg of Protein) | LPO (TBARS-nM/min/mg Protein) | |
|---|---|---|---|---|
| Sham | 4.089 ± 1.84 | 40.36 ± 1.09 | 83.4 ± 0.48 | 41.5 ± 0.42 |
| p-MCAO | 13.35 ± 2.48 ** | 13.51 ± 0.75 *** | 14.28 ± 0.48 *** | 118.8 ± 0.73 *** |
| A3+p-MCAO (10mg/kg) | 5.63 ± 0.92 ## | 26.04 ± 2.11 ### | 40 ± 1.23 ### | 64.3 ± 0.52 ### |
| ATRA+p-MCAO | 17.84 ± 1.2 | 14.9 ± 1.83 | 20 ± 1.97 | 111.3 ± 0.52 ## |
| A3+ATRA+p-MCAO | 15.45 ± 0.69 | 13.14 ± 2.06 | 18.4 ± 1.24 | 113 ± 0.42 ## |
Symbols *** or ### indicates significant difference at p < 0.001, while ** and ## indicates significant difference at p < 0.01, respectively. *** vs. sham, # vs. p-MCAO group. The data are presented as mean ± SEM, with n = 5/group. The symbol * shows a significant difference vs. sham and # shows the significant difference vs. p-MCAO. Abbreviations: NO, nitric oxide; GST, glutathione S-transferase; GSH, reduced glutathione; LPO, lipid peroxidation; TBARS, thiobarbituric acid reactive substances.