Table 1.
Blood biochemical analysis, lipid profile values, results of oral glucose tolerance test (OGTT) and Visceral Adiposity Index (VAI) values in adolescents with polycystic ovary syndrome (PCOS) and “healthy” girls.
| Parameters | PCOS Group (n = 130) | Control Group (n = 30) | p-Level |
|---|---|---|---|
| Protein total *, g/L | 72.2 (69.7–76.1) | 70.6 (69.7–72.1) | 0.0362 |
| Urea *, mmol/L | 4.0 (3.2–4.7) | 4.5 (3.4–4.6) | 0.7195 |
| Creatinine *, μmol/L | 75.6 (68.4–84.6) | 74.4 (67.0–83.4) | 0.9941 |
| Bilirubin total, μmol/L | 12.2 (9.5–18.2) | 10.6 (8.3–14.0) | 0.0789 |
| Bilirubin direct, μmol/L | 4.0 (2.7–5.2) | 2.9 (2.4–3.8) | 0.0289 |
| Calcium *, mmol/L | 2.4 (2.3–2.5) | 2.4 (2.3–2.4) | 0.4003 |
| Magnesium *, mmol/L | 0.8 (0.7–0.8) | 0.6 (0.6–0.7) | 0.0054 |
| Iron *, μmol/L | 18.0 (11.6–24.3) | 15.6 (10.9–19.6) | 0.2107 |
| Cholesterol *, mmol/L | 4.3 (3.9–5.0) | 3.9 (3.5–4.7) | 0.2511 |
| TG *, mmol/L | 0.8 (0.6–1.2) | 0.7 (0.7–0.9) | 0.3366 |
| HDL *, mmol/L | 1.4 (1.2–1.6) | 1.6 (1.2–1.9) | 0.0813 |
| LDL *, mmol/L | 2.1 (1.7–2.7) | 1.9 (1.6–2.4) | 0.2716 |
| Atherogenic index * | 2.1 (1.6–2.8) | 1.7 (1.4–1.9) | 0.0513 |
| Glucose 0’ *, mmol/L | 5.0 (4.7–5.3) | 5.0 (4.6–5.2) | 0.5548 |
| Glucose 120’ *, mmol/L | 6.0 (5.3–6.9) | – | – |
| Insulin 0’ *, mIU/ml | 13.3 (8.7–19.3) | 11.0 (8.2–11.9) | 0.2306 |
| Insulin 120’ *, mIU/ml | 30.4 (14.4–47.4) | – | – |
| НОМА–IR * | 2.9 (1.8–4.1) | 2.3 (1.9–2.8) | 0.2886 |
| VAI * | 1.0 (0.6–1.6) | 0.7 (0.5–1.0) | 0.0461 |
| CRP *, mg/L | 0.6 (0.2–1.3) | 0.8 (0.3–1.3) | 0.4772 |
* variable with a non-normal distribution, data are presented as median (25–75 percentiles), Mann–Whitney U-test. TG: triglycerides; LDL: low-density lipoproteins; HDL: high-density lipoproteins; HOMA-IR: Homeostasis Model Assessment of Insulin Resistance; CRP: highly sensitive C-reactive protein.