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Overlay of three color-coded pain-related terms. “Chronic pain” is blue, “painful” is yellow, and “pain” is red. Functional magnetic resonance imaging (fMRI) studies of these terms are visualized in coronal (a), axial (b), and sagittal (c) axes from the Neurosynth database (neurosynth.org), showing consistent activation of the anterior cingulate cortex (ACC), thalamus, insula, and brainstem.
