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Size (bars), PdI, and Zeta-potential (lines and symbols) of Imiquimod-loaded CS (A,B), INU:Ag:pArg and INU:pArg:Ag (C,D) nanocapsules stored at 4 °C at different time points. Due to the reduced stability of the CS nanocapsules after antigen adsorption (Figure S1), the nanocapsules were tested in the absence of the antigen. Size and PdI were measured in ultrapure water and Zeta-potential in 1 mM KCl. Ag: Antigen, CS: Chitosan, INU: Inulin, pArg: Polyarginine.
