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Temporal trend of the sepsis rate (regarding all hospital admissions with a diagnosis of chronic HCV infection, %) and the sepsis-related death (regarding chronic HCV-infected patients with (A) hospital admission and sepsis, (B) CFR, %) in Spain (2000–2015). Statistic: Values were expressed as percentages. The Extended Mantel Haenszel Chi-Square was used to calculate the linear trend from 2000–2003 to 2012–2015. Abbreviations: HCV, hepatitis C virus; CFR, case-fatality rate.
