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. 2020 Jun 20;4(2):32. doi: 10.3390/vision4020032
Day 0 Subjective (eligibility) and objective evaluation.
Day 1–7 Loratadine 10 mg upon waking in AM, placebo at noon, placebo at 6 PM.
Day 8 Objective evaluation.
Day 8–14 Washout period.
Day 14 Objective evaluation.
Day 15–21 Diphenhydramine 25 mg upon waking in AM, at noon, and at 6 PM.
Day 22 Objective evaluation.
Day 22–28 Washout period.
Day 28 Objective evaluation.
Day 29–35 Placebo upon waking in AM, noon, and at 6 PM.
Day 36 Objective evaluation.