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. 2020 Jun 8;9(6):1779. doi: 10.3390/jcm9061779

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Example of ^99mTc-HMPAO WBC scintigraphy in a patient with a skin ulcer in the medial right malleolus region, previous amputations of left leg, and of all metatarsal heads of the right foot. From left to right: Planar images acquired after 30 min, 3 h, and 20 h p.i. of radiolabelled autologous leukocytes show an increased amount of activity over time in terms of intensity and extent, being consistent with OM with an involvement of adjacent soft tissues. Further SPECT/CT acquisition (right panel) correctly localized the uptake in the right talus and accurately evaluated its extent into surrounding soft tissues. HMPAO: hexamethylpropylene amine oxine, WBC: white blood cell.