Table 3.

Histopathological lesion scores of the heart and liver of infected and control groups at two and seven days post infection.

DPI 1	Group 2	Heart Lesion Scores 3			Liver Lesion Scores
		Pericarditis	Myocarditis	Myocardial Necrosis (Hyalinosis)	Necrosis of Hepatocytes	Inflammation in the Portal Area	Inflammation in the Hepatic Parenchyma	Congestion	Glisson’s Capsule Leucocytic Infiltration
2	NC	-	-	+	-	-	-	+	-
	CBL-V/O78-C	+	+	+	+	+/++	+/++	+	-
	CBL-V/O125-C	++	++	+++	+	+/++	+/++	++	-
	Lector/O78-C	-	-	+	++	++	++	++	-
	Lector/O125-C	-/+	+	+	++	++	++	++	-
	PC-O78	+++	+	++	++	++	++	++	-
	PC-125	++	++	++	++	++	++	++	-
7	NC	-	-	-/+	-/+	-	-	-/+	-
	CBL-V/O78-C	-/+	+	-/+	+/++	+/++	+/++	++	-
	CBL-V/O125-C	+/++	+/++	+/++	++	++	++	++	-
	Lector/O78-C	+	-/+	+	++	++	++	+++	-
	Lector/O125-C	-/+	+	+	++	++	+++	++	-
	PC-O78	+++	+++	+++	+++	+++	+++	+++	++
	PC-125	+++	++	+++	+++	+++	+++	+++	++

¹ DPI: days post infection. ² Groups: NC—negative control, CBL-V—vaccinated, not challenged; CBL-V/O₇₈-C—vaccinated, challenged with E. coli O₇₈; CBL-V/O₁₂₅-C—vaccinated, challenged with E. coli O₁₂₅; Lector+O₇₈-C—lector three days before challenge with E. coli O₇₈; Lector+O₁₂₅-C—lector three days before challenge with E. coli O₁₂₅; PC-O₇₈—positive control E. coli O₇₈ challenge; PC-O₁₂₅—positive control E. coli O₁₂₅. ³ Lesions were scored as (-)—no lesion, (-/+)—minimal, (+)—mild, (++)—moderate, and (+++)—severe.