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. 2020 Jun 8;9(6):1782. doi: 10.3390/jcm9061782

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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L-arginine/NO pathway metabolites as RoBF ≥ 5 predictors: (a) Arg-Δ_24/0; (b) Arg-Δ_72/24; (c) ADMA-Δ_72/0; (d) ADMA-Δ_72/24; (e) SDMA-Δ_72/0; (f) SDMA-Δ_72/8; (g) SDMA-Δ_72/24; (h) a panel consisting of Arg-Δ_24/0, Arg-Δ_72/0, ADMA-Δ_24/8, and SDMA-Δ_72/24—ratios of metabolites selected in the logistic regression analysis as variables independently from others associated with delayed restoration of bowel function (RoBF ≥ 5 days); (i) Arg/ADMA-Δ_24/0. Arg: Arginine; ADMA: Asymmetric dimethylarginine; SDMA: Symmetric dimethylarginine; AUC: Area under receiver operating characteristic (ROC) curve. Data presented as AUC with a 95% confidence interval and p-value for difference from AUC = 0.5 characterizing a chance marker.