Table 12.
Characteristics of L-arginine/NO pathway metabolites as predictors of surgical site infections.
| Marker | Criterion | Sens. and Spec. | Youden (J) Index | LR+ and LR− |
|---|---|---|---|---|
| Arg-Δ24/0 | ≤0.84 | 91.7 and 40% | 0.317 | 1.5 and 0.21 |
| Arg-Δ72/0 | ≤1.44 | 100 and 32.6% | 0.326 | 1.5 and 0 |
| ADMA-Δ24/8 | ≤1.0 | 100 and 43.2% | 0.432 | 1.8 and 0 |
| SDMA-Δ72/24 | >1.08 | 50 and 93.2% | 0.430 | 7.2 and 0.54 |
| Panel 1 | >0.1 2 | 100 and 68.3% | 0.683 | 3.2 and 0 |
| Arg/ADMA-Δ24/0 | ≤0.904 | 75 and 55.6% | 0.306 | 1.7 and 0.45 |
| Arg/ADMA-Δ72/0 | ≤1.131 | 63.6 and 72.1% | 0.357 | 2.3 and 0.5 |
Sens.: Sensitivity; Spec.: Specificity; LR: Likelihood ratios; Arg: Arginine; ADMA: Asymmetric dimethylarginine; SDMA: Symmetric dimethylarginine; 1 a metabolite panel consisting of Arg-Δ24/0, Arg-Δ72/0, ADMA-Δ24/8, and SDMA-Δ72/24; 2 predicted probabilities.