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. 2020 May 27;12(6):486. doi: 10.3390/pharmaceutics12060486

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Membrane transporters expressed in hepatocytes. Transporters indicated in green have been described in the literature to transport [^99mTc]mebrofenin. BCRP = Breast Cancer Resistance Protein, BSEP = Bile-Salt Export Pump, MATE1 = Multidrug And Toxin Extrusion Protein 1, MRP = Multidrug Resistance-Associated Protein, NTCP = Na⁺-taurocholate-cotransporting polypeptide, OAT = Organic Anion Transporter, OATP = Organic Anion-Transporting Polypeptide, OCT = Organic Cation Transporter, OST = Organic Solute Transporter, P-gp = P-glycoprotein.