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. 2020 Jun 7;9(6):1771. doi: 10.3390/jcm9061771

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Changes in estimated glomerular filtration rate (eGFR) after tacrolimus (TAC) discontinuation. (a) Changes in eGFR in overall patient population. Changes in renal function were analyzed in 23 patients treated with TAC for more than 6 months and whose course could be followed for more than 1 year after discontinuation of TAC treatment. * p < 0.05 (analyzed using Mann–Whitney test). (b) Changes in eGFR in patients with eGFR reductions less than 30% (n = 12) and in patients with eGFR reductions more than 30% (n = 11) after administration. * p < 0.05 (analyzed using Mann–Whitney’s test).