Table 3.
The inhibitory effect of NZ surf clam extracts after an incubation time of 72 h.
| Cell line | % Cell viability: Oven dried (OD) treatment |
% Cell viability: Freeze-dried (FD) treatment |
||||||
|---|---|---|---|---|---|---|---|---|
| 250 μg/ml | 500 μg/ml | 1000 μg/ml | 250 μg/ml | 500 μg/ml | 1000 μg/ml | |||
| A549 | DScd | 76 | 76 | 82 | DSea | 64∗ | 44∗∗ | 8∗∗∗∗ |
| SSea | 107 | 68 | 15 | SSea | 80∗∗ | 59∗ | 19NS | |
| TTpe | 106 | 113 | 45 | TTea | 87 ∗∗ | 35∗∗∗ | 11∗∗∗ | |
| Hep G2 | DSet | 92 | 69 | 31 | DSea | 87 NS | 65 NS | 9∗∗∗ |
| SSpe | 61∗∗∗ | 38∗∗∗ | 19 | SSea | 108 | 84 | 15 NS | |
| TTpe | 161 | 140 | 49 | TTea | 115∗∗∗ | 24∗∗∗∗ | 18∗∗∗ | |
| MCF-7 | DSea | 57∗ | 20∗∗∗ | 24 | DSpe | 68 | 44 | 15∗ |
| SSpe | 114 | 15 | 15 | SScd | 59∗∗∗ | 16 NS | 8∗ | |
| TTpe | 112 | 20 | 14 | TTpe | 64∗∗∗ | 14 NS | 14 NS | |
| MIA PaCa-2 | DSea | 49 | 11 | 11 | DSea | 21∗∗∗ | 11 NS | 11 NS |
| SSea | 138 | 22∗∗ | 14 | SSea | 84∗∗∗ | 40 | 12 NS | |
| TTpe | 97 | 106 | 62 | TTpe | 40∗ | 12∗∗∗∗ | 14∗∗∗ | |
| PC-3 | DSea | 15∗∗∗ | 10∗∗∗ | 13∗ | DSpe | 72 | 62 | 23 |
| SSet | 74 | 12∗∗ | 12∗ | SSpe | 53∗∗∗ | 30 | 20 | |
| TTet | 91 | 61 | 28 | TTpe | 79∗ | 54∗ | 16∗ | |
| SiHa | DSpe | 87∗∗ | 36 | 31 | DSea | 107 | 21∗∗ | 21∗ |
| SSpe | 46∗∗∗ | 46 | 40 | SSea | 85 | 38∗ | 18∗∗∗ | |
| TTpe | 70 | 24 | 32 | TTpe | 69 NS | 23 NS | 18∗ | |
| WiDr | DSea | 20∗∗∗ | 6∗∗∗ | 6∗ | DSpe | 53 | 27 | 14 |
| SSet | 72 | 11∗ | 5∗ | SSpe | 34∗∗∗ | 23 | 13 | |
| TTet | 54 | 24 | 17 | TTpe | 55 NS | 16∗ | 15 NS | |
OD, Oven dried; FD, Freeze dried; Experiments were carried out twice, in triplicates. Data is presented as means ± SE. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.005; ∗∗∗∗p < 0.0005; NS = not significant (Student's t-test).