Figure 2.
Structure of lipid nanoparticles (LNPs) comprising of all the components. An overall structural arrangement of lipid components used to formulate LNPs is shown. LNPs comprise of 4 main lipid components namely, ionizable lipids (pink), phospholipids (light yellow), polyethylene glycol (PEG)ylated lipids (light blue), and cholesterol (orange) encapsulating nucleic acid cargo such as double-stranded siRNA or single-stranded mRNA or antisense oligonucleotide (ASO).