Table 4.
Mutations of SeSCar (strain evolved by cyclic exposure to prolonged sublethal treatments of carvacrol) in comparison with Salmonella enterica subsp. enterica serovar Typhimurium LT2 wild type (SeWT), verified by Sanger sequencing. Single nucleotide variation (SNV), insertion (Ins) and deletion (Del).
| Genome Position | Gene | Locus Tag | Mutation * | Change | Information |
|---|---|---|---|---|---|
| 290,313 | rrsH | STM0249 | SNV: G1124A | No coding | RNA 16S ribosomal |
| 290,319 | rrsH | STM0249 | SNV: C1130T | No coding | RNA 16S ribosomal |
| 290,718 | rrsH | STM0249 | SNV: A1529C | No coding | RNA 16S ribosomal |
| 506,753 | lon | STM0450 | SNV: G1211A | Gly404Asp | Protease |
| 643,922 | fepA | STM0585 | Ins: + TTTGCA 107 | No coding | Membrane receptor protein |
| 2683,182 | yfhP | STM2544 | SNV: C245A | Ala82Glu | HTH IscR transcriptional regulator |
| 3626,869 | nirC | STM3476 | SNV: T215C | Val72Ala | Membrane transport protein (Nitrite transport) |
* Position with respect to the start of the coding region.