Table 3.
Performance of clinical risk scores at emergency department admission to predict severe disease from covid-19, n = 66
| Sensitivity % (95% CI) |
Specificity % (95% CI) |
PPV % (95% CI) |
NPV % (95% CI) |
AUC (95% CI) |
|
|---|---|---|---|---|---|
| NEWS2 ≥ 5 | 86.7 (59.5–98.3) | 70.6 (56.2–82.5) | 46.4 (35.2–58.1) | 94.7 (83.0–98.5) | 0.786 (0.659–0.913) |
| NEWS2 ≥ 6 | 80.0 (52.9–95.7) | 84.3 (71.4–92.9) | 60.0 (43.1–74.8) | 93.5 (83.8–97.5) | 0.822 (0.690–0.953) |
| qSOFA ≥ 2 | 26.7 (7.8–55.1) | 98.0 (89.6–100.0) | 80.0 (32.6–97.1) | 82.0 (77.0–86.1) | 0.624 (0.446–0.810) |
| ≥2 SIRS criteria | 60.0 (32.3–83.7) | 66.7 (52.1–79.2) | 34.6 (23.1–48.3) | 85.0 (74.8–91.6) | 0.633 (0.470–0.796) |
| CRB-65 ≥ 2 | 26.7 (7.8–55.1) | 90.2 (78.6–96.7) | 44.4 (19.7–72.3) | 80.7 (75.3–85.2) | 0.584 (0.410–0.759) |
CI, Confidence interval; PPV, Positive Predictive Value; NPV, Negative Predictive Value; AUC, Area under the Curve; NEWS, National Early Warning Score; qSOFA, Quick Sequential Organ Failure Assessment; SIRS, Systemic Inflammatory Response Syndrome