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. 2020 Jul 13;5:125. doi: 10.1038/s41392-020-00233-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Diseases caused by dysfunction of stress proteins and their dysregulation by virus infections. The left panel shows the expression level of stress proteins in diverse human diseases, including cancers and neurodegenerative diseases. The expression level of stress proteins is significantly elevated in cancer cells but dramatically decreased in neurodegenerative disease. The right panel shows the virus infection-caused diseases from mild to severe which include cancers and neurodegenerative diseases. Stress proteins contribute to these diseases