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. 2020 Jul 13;5:125. doi: 10.1038/s41392-020-00233-4

Table 3.

Hsp60 inhibitors

Types Inhibitors Mechanism and references
Natural Products Mizoribine To inhibit chaperone activity of the Hsp60-Hsp10 complex; to block ATP binding and hydrolysis33
Epolactaene To inhibit chaperone activity of the Hsp60-Hsp10 complex683
Myrtucommulone A (MC) To inhibit chaperone activity of the Hsp60-Hsp10 complex686
Stephacidin B Undetermined694
Avrainvillamide Undetermined695
Synthetic Compounds O-carboranyl-phenoxyacetanilide To inhibit chaperone activity of the Hsp60-Hsp10 complex; to block ATP binding and hydrolysis685
Gold porphyrins To inhibit chaperone activity of the Hsp60-Hsp10 complex