Figure 3.
Penetration of the IMQ-induced psoriatic skin by the near infra-red (NIR) ABP-NIR dendrimer, a fluorescent analogue of the ABP dendrimer. First column shows the nuclear 4’,6-diamidino-2-phenylindole (DAPI) staining, second column shows the near infra-red fluorescence of the ABP-NIR dendrimer, third column shows the merge of the first two columns, and last column shows bright field imaging of (A) skin incubated with phosphate-buffered saline (PBS; control), and (B) day 5 and (C) day 7 psoriatic skins incubated with the ABP-NIR dendrimer (two mice each). Scale bars represent 50 µm.
