Skip to main content
. 2020 Jun 19;9(6):1918. doi: 10.3390/jcm9061918
NSCLC Non-small cell lung cancer
RTK Receptor tyrosine kinase
RAS Rat sarcoma virus
RAF Serine/threonine-protein kinase
KRAS Kirsten rat sarcoma
EGFR Epidermal growth factor receptor
BRAF v-Raf murine sarcoma viral oncogene homolog B
MET Mesenchymal-epithelial transition
PI3K Phosphoinositide 3-kinase
HGF Hepatocyte growth factor
MAPK Mitogen-activated protein kinase
FISH Fluorescent in-situ hybridization
TKI Tyrosine-kinase inhibitors
PFS Progression-free survival
OS Overall survival
ORR Overall response rate
HR Hazard ratio
CI Confidence interval
IV Intravenous
IHC Immunohistochemistry
DCR Disease control rate
DOR Duration of response
CNS Central nervous system