Figure 5.

Milk EVs can be engineered to be used as drug-delivery system. Schematic representation of the (A) advantages of using milk EVs as drug-delivery system and (B) macromolecules that can be packaged and delivered via milk EVs. The nanosized vesicles, other than their intrinsic cargo, can also serve to deliver a variety of molecules including chemotherapeutic and anti-inflammatory drugs, recombinant proteins, peptides and nucleic acids. These EVs can be engineered to target specific sites of interest with the help of targeting ligands and lipids on their surface.