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Optimized variables levels of the optimized FLB niosomes and its predicted and observed responses.
| Variables | X1: Span® 85 conc. (µM) | X2: Hydration Time (min.) | X3: Hydrating Buffer pH |
|---|---|---|---|
| Optimum values | 6.0 | 60.0 | 6.6 |
| Predicted Value | Observed Value | Error % | |
| Vesicle size (nm) | 49.15 | 46.35 | 5.69 |
| Entrapment efficiency (%) | 95.45 | 92.48 | 3.18 |
Abbreviations: FLB, Flibanserin.
