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. 2020 Jun 25;25(12):2921. doi: 10.3390/molecules25122921

Table 3.

Hepatic lipid accumulation in rats fed experimental diets.

Liver Mass Fat Content Cholesterol TG α-Linolenic Acid (omega-3) Linoleic Acid (omega-6) Oleic Acid (omega-9)
g/100 g BW % mg/g liver mg/g liver mg/g liver
Group 1
LC (n = 8) 4.80 ± 0.03 7.36 ± 0.50 1.15 ± 0.02 d 6.62 ± 0.72 0.07 ± 0.01 b 8.03 ± 0.55 b 8.51 ± 0.43
LPO (n = 8) 4.82 ± 0.14 7.04 ± 0.28 1.26 ± 0.05 d 5.81 ± 0.82 0.28 ± 0.02 b 21.49 ± 1.11 a 9.56 ± 0.27
LHO (n = 8) 4.91 ± 0.06 7.35 ± 0.43 1.17 ± 0.05 d 4.30 ± 0.52 2.13 ± 0.11 a 21.13 ± 0.63 a 8.64 ± 0.18
OC (n = 6) 5.53 ± 0.45 23.3 ± 1.98 1.87 ± 0.02 a 25.7 ± 2.37 0.12 ± 0.01 b 6.36 ± 0.45 b 5.84 ± 0.39
OPO (n = 6) 5.92 ± 0.46 23.2 ± 2.87 1.67 ± 0.09 b 26.0 ± 3.35 0.16 ± 0.01 b 8.74 ± 0.54 b 5.66 ± 0.25
OHO (n = 6) 6.05 ± 0.34 26.0 ± 2.93 1.45 ± 0.02 c 25.9 ± 1.99 0.45 ± 0.04 b 7.31 ± 0.71 b 6.08 ± 0.44
Oil type (O)
Control (n = 14) 5.11 14.22 1.46 14.81 0.10 7.20 7.18
Poppy seed oil (n = 14) 5.29 14.01 1.44 14.52 0.22 15.12 7.62
Hemp seed oil (n = 14) 5.40 15.42 1.29 13.62 1.29 14.22 7.37
p value NS NS <0.01 NS <0.001 <0.001 NS
Zucker phenotype (T)
Lean (n = 24) 4.84 7.25 1.19 5.57 0.83 16.89 8.91
Obese (n = 18) 5.83 24.21 1.66 25.91 0.25 7.47 5.87
p value <0.05 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
Interaction O × T
p value NS NS <0.001 NS <0.01 <0.001 NS

Values are the mean ± SEM. NS, p > 0.05; TG, triglycerides. 1 LC, lean rats fed a control diet with palm oil; LPO, lean rats fed a diet with poppy seed oil; LHO, lean rats fed a diet with hemp seed oil; OC, obese rats fed a control diet with palm oil; OPO, obese rats fed a diet with poppy seed oil; OHO, obese rats fed a diet with hemp seed oil. a–d Mean values within a column with different superscript letters were shown to be significantly different (p < 0.05); differences among the groups are only indicated with superscripts in the case of a statistically significant interaction O × T and differences between the oil type (p ≤ 0.05).