Table 4.

Cut-off ratios of white matter/cortex perfusion values of relative cerebral blood volume (rBV), relative cerebral blood volume corrected for leakage (rBVc), relative cerebral blood flow (rBF) and mean transit time (MTT) calculated by ROC analysis.

	oSVD				Bayesian
	rBV	rBVc	rBF	MTT	rBV	rBVc	rBF	MTT
left frontal
Cut off ratio	0.4	0.36	0.29	1.18	0.41	0.36	0.21	1.39
Sensitivity	83%	83%	83%	83%	83%	83%	83%	67%
specificity	75%	80%	65%	55%	75%	80%	45%	60%
AUC	0.908 *	0.833 *	0.825 *	0.650	0.917 *	0.833 *	0.708	0.567
right frontal
Cut off ratio	0.33	0.3	0.27	1.18	0.33	0.30	0.21	0.92
Sensitivity	60%	60%	60%	80%	60%	60%	60%	60%
specificity	42.9%	43%	47.6%	47.6%	42.9%	42.9%	47.6%	14.4%
AUC	0.667	0.657	0.667	0.514	0.667	0.657	0.543	0.581
left parietal
Cut off	0.66	0.91	0.87	-	0.66	0.91	0.77	-
Sensitivity	50%	50%	50%	-	50%	50%	50%	-
specificity	95.8%	100%	100%	-	58%	100%	100%	-
AUC	0.479	0.521	0.542	0	0.479	0.521	0.688	0.021
right parietal
Cut off ratio	0.65	0.97	0.91	-	0.67	0.97	0.83	-
Sensitivity	66.7%	66.7%	66.7%	-	66.7%	66.7%	66.7%	-
specificity	82.6%	100%	100%	-	87%%	100%	100%	-
AUC	0.609	0.667	0.667	0.203	0.609	0.681	0.739	0.072
left temporal
Cut off ratio	0.73	0.55	0.85	1.03	0.77	0.55	0.42	1.47
Sensitivity	50%	50%	25%	75%	50%	50%	75%	75%
specificity	77.3%	72.7%	100%	50%	77.3%	72.7%	59.1%	54.5%
AUC	0.591	0.545	0.466	0.568	0.602	0.557	0.625	0.602
right temporal
Cut off ratio	0.47	0.43	0.45	1.03	0.47	0.43	0.35	1.4
Sensitivity	75%	75%	75%	75%	100%	75%	75%	50%
specificity	50%	59.1%	63.6%	36.4%	45.5%	59.1%	54.5%	63.6%
AUC	0.659	0.591	0.716	0.466	0.625	0.602	0.648	0.432

AUC = area under the curve, significant results (p < 0.05) are marked with *.