Table 2.
Concomitant diseases in IPAH and CHD-PAH.
| Disease | All Patients | IPAH | CHD-PAH | P |
|---|---|---|---|---|
| N = 80 | N = 25 | N = 54 | ||
| Hypertension | 2 | 2 | 0 | 0.04 |
| Smoking | 1 | 0 | 1 | 0.5 |
| Asthma | 2 | 1 | 1 | 0.57 |
| Hypothyroidism | 19 | 3 * | 16 * | 0.09 |
| Hyperthyroidism | 2 | 0 | 2 | 0.33 |
| Atrial flutter | 1 | 0 | 1 | 0.5 |
| Down syndrome * | 24 | 2 | 22 | 0.004 |
| Mental retardation | 32 | 5 | 27 | 0.01 |
| History of acute PE | 1 | 1 | 0 | 0.14 |
| Inflammatory bowel disease | 2 | 1 | 1 | 0.57 |
| Cardiac stimulation | 1 | 0 | 1 | 0.5 |
| Sleep apnea | 1 | 1 | 0 | 0.14 |
| Preterm < 36 week | 4 | 3 | 1 | 0.06 |
* Down syndrome was present in one IPAH patient with hypothyroidism and in 15 patients with CHD-PAH with hypothyroidism; PE, pulmonary embolism.