Table 2.
Adverse events.
| Any Grade | Grade 3–4 | |
|---|---|---|
| All adverse events > 15%, n (%) | ||
| Anemia | 27 (75.0) | 0 (0.0) |
| Hypoalbuminemia | 27 (75.0) | 0 (0.0) |
| Platelet count decreased | 21 (58.3) | 0 (0.0) |
| Neutrophil count decreased | 15 (41.7) | 1 (2.8) |
| Paronychia | 15 (41.7) | 0 (0.0) |
| Decreased appetite | 15 (41.7) | 4 (11.1) |
| Diarrhea | 15 (41.7) | 1 (2.8) |
| White blood cell decreased | 14 (38.9) | 1 (2.8) |
| Aspartate aminotransferase increased | 14 (38.9) | 2 (5.6) |
| Fatigue | 13 (36.1) | 3 (8.3) |
| Dermatitis acneiform | 13 (36.1) | 0 (0.0) |
| Alanine aminotransferase increased | 11 (30.6) | 0 (0.0) |
| Alkaline phosphatase increased | 11 (30.6) | 2 (5.6) |
| Creatinine increased | 11 (30.6) | 0 (0.0) |
| Pruritus | 8 (22.2) | 0 (0.0) |
| Mucositis oral | 8 (22.2) | 0 (0.0) |
| Grade 3–4 adverse events, n (%) | ||
| Pneumonitis | 4 (11.1) | 2 (5.6) |
| Left ventricular systolic dysfunction | 1 (2.8) | 1 (2.8) |
| Electrocardiogram QT prolongation | 1 (2.8) | 1 (2.8) |
| Delirium | 1 (2.8) | 1 (2.8) |
| Hallucination | 1 (2.8) | 1 (2.8) |
| Dyspnea | 1 (2.8) | 1 (2.8) |
| Dehydration | 1 (2.8) | 1 (2.8) |
| Lung infection | 2 (5.6) | 1 (2.8) |
| Sinusitis | 1 (2.8) | 1 (2.8) |