Table 2.
Comparison of characteristics between subjects with and without NAFLD.
| Before PS Matching | After PS Matching | |||||
|---|---|---|---|---|---|---|
| Non-NAFLD | NAFLD | p-Value | Non-NAFLD | NAFLD | p-Value | |
| n | 2571 | 1154 | 1097 | 1097 | ||
| BMI (kg/m2) | 22.0 ± 2.7 | 25.8 ± 3.3 | <0.001 | 22.4 ± 2.7 | 25.7 ± 3.2 | <0.001 |
| Obesity | 320 (12.4) | 635 (55.0) | <0.001 | 175 (16.0) | 590 (53.8) | <0.001 |
| Smoking | <0.001 | 0.008 | ||||
| Never | 1846 (71.8) | 626 (54.2) | 678 (61.8) | 613 (55.9) | ||
| Past | 476 (18.5) | 352 (30.5) | 261 (23.8) | 321 (29.3) | ||
| Current | 249 (9.7) | 176 (15.3) | 158 (14.4) | 163 (14.9) | ||
| Systolic BP (mmHg) | 121.9 ± 15.2 | 130.0 ± 14.5 | <0.001 | 124.7 ± 14.7 | 129.5 ± 14.4 | <0.001 |
| Diastolic BP (mmHg) | 72.7 ± 11.2 | 80.0 ± 10.8 | <0.001 | 75.2 ± 11.0 | 79.2 ± 10.8 | <0.001 |
| Hypertension | 520 (20.2) | 459 (39.8) | <0.001 | 321 (29.3) | 406 (37.0) | <0.001 |
| AST level (IU/L) | 21 ± 6 | 25 ± 10 | <0.001 | 21 ± 5 | 25 ± 10 | <0.001 |
| ALT level (IU/L) | 19 ±10 | 33 ± 21 | <0.001 | 21 ± 9 | 33 ± 21 | <0.001 |
| GGT level (IU/L) | 24 ± 22 | 41 ± 36 | <0.001 | 28 ± 25 | 40 ± 35 | <0.001 |
| Triglyceride level (mg/dL) | 87 ± 47 | 146 ± 92 | <0.001 | 94 ± 44 | 146 ± 93 | <0.001 |
| High triglyceride level | 192 (7.5) | 399 (34.6) | <0.001 | 107 (9.8) | 376 (34.3) | <0.001 |
| Total cholesterol level (mg/dL) | 210 ± 32 | 213 ± 34 | 0.004 | 208 ± 32 | 214 ± 93 | <0.001 |
| HDL cholesterol level (mg/dL) | 65 ± 15 | 53 ± 11 | <0.001 | 62 ± 15 | 53 ± 11 | <0.001 |
| LDL cholesterol level (mg/dL) | 124 ± 29 | 135 ± 30 | <0.001 | 125 ± 28 | 136 ± 30 | <0.001 |
| High LDL cholesterol level | 726 (28.2) | 478 (41.4) | <0.001 | 318 (29.0) | 466 (42.5) | <0.001 |
| Fasting glucose level (mg/dL) | 95 ± 15 | 105 ± 19 | <0.001 | 98 ± 16 | 105 ± 18 | <0.001 |
| Diabetes mellitus | 90 (3.5) | 134 (11.6) | <0.001 | 59 (5.4) | 113 (10.3) | <0.001 |
| Uric acid level (mg/dL) | 4.8 ± 1.2 | 5.8 ± 1.2 | <0.001 | 5.2 ± 1.2 | 5.8 ± 1.3 | <0.001 |
| Hyperuricemia | 131 (5.1) | 199 (17.2) | <0.001 | 85 (7.7) | 191 (17.4) | <0.001 |
| SCr level | 0.74 | 0.81 | <0.001 | 0.81 | 0.81 | 0.742 |
| eGFR | 74.7 | 73.1 | <0.001 | 73.5 | 73.3 | 0.719 |
| CKD | 239 (9.3) | 146 (12.7) | 0.002 | 127 (11.6) | 138 (12.6) | 0.471 |
Values are expressed as the mean ± standard deviation or number (%). BMI, body mass index; BP, blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyl transferase; HDL, high-density lipoprotein; LDL, low-density lipoprotein; SCr, serum creatinine; eGFR, estimated glomerular filtration rate; CKD, chronic kidney disease; NAFLD, non-alcoholic fatty liver disease; PS, propensity score.