Table 4.
Indicator | Number of Animals | Groups | ||||
---|---|---|---|---|---|---|
Group I | Group II | Control | Group III | Intact Animals | ||
1 | 2 | 3 | 4 | 5 | 6 | 7 |
Total number of appearances in the dark chamber | 1 | 2 ± 0.24 *,** | 1.14 ± 0.36 ** | 1.14 | 1.43 ± 0.42 * | 1.71 |
2 | 1.71 ± 0.20 ** | 1.43 ± 0.10 ** | 2.14 | 0.57 ± 0.04 * | 1.71 | |
3 | 1.43 ± 0.29 * | 2.29 ± 0.05 * | 0.71 | 0.86 ± 0.71 * | 1.43 | |
4 | 1.86 ± 0.14 * | 1.29 ± 0.28 ** | 1.29 | 0.57 ± 0.41 * | 1.86 | |
5 | 1.57 ± 0.36 * | 1.29 ± 0.79 ** | 1.29 | 1.43 ± 1 * | 1.14 | |
Σ 1–5 | 8.57 ± 0.31 ** | 7.43 ± 0.20 ** | 6.57 | 4.86 ± 0.29 * | 7.86 | |
Total time of staying in the dark branches of the maze, s | 1 | 19 ± 0.01 ** | 18.14 ± 0.17 ** | 18.86 | 40.71 ± 0.10 * | 45.57 |
2 | 23.57 ± 0.09 ** | 18.43 ± 0.02 ** | 24.43 | 40.86 ± 0.17 * | 45.57 | |
3 | 23.71 ± 0.02 ** | 33.43 ± 0.12 ** | 22.71 | 44.43 ± 0.24 * | 51.86 | |
4 | 23.14 ± 0.02 ** | 32.71 ± 0.24 ** | 21.86 | 47.14 ± 0.11 * | 46.14 | |
5 | 13.86 ± 0.02 ** | 33.57 ± 0.17 ** | 22.71 | 42.57 ± 0.04 * | 54.57 | |
Σ 1–5 | 103.29 ± 0.02 ** | 136.29 ± 0.04 ** | 110.57 | 215.71 ± 0.09 * | 243.71 | |
Total number of appearances in the central location | 1 | 2.86 ± 0.24 ** | 2.29 ± 0.58 * | 2 | 2 ± 1 * | 1.43 |
2 | 3.14 ± 0.40 ** | 2.57 ± 0.34 ** | 2.86 | 1.86 ± 0.20 * | 2.43 | |
3 | 2.14 ± 0.35 ** | 2.29 ± 0.27 ** | 2 | 1.14 ± 0.10 * | 1.14 | |
4 | 3.43 ± 0.07 ** | 2 ± 0.60 * | 2.14 | 1.14 ± 0.22 * | 2.43 | |
5 | 2.57 ± 0.23 ** | 1.14 ± 0.20 * | 2.29 | 1.72 ± 0.68 * | 1 | |
Σ 1–5 | 14.14 ± 0.12 ** | 10.29 ± 0.49 ** | 11.29 | 7.86 ± 0.31 * | 8.43 | |
Total number of appearances in the illuminated branches of the maze | 1 | 1.57 ± 0.22 ** | 1 ± 0.36 ** | 1.14 | 0.71 ± 0.10 * | 0.86 |
2 | 0.86 ± 0.46 ** | 0.86 ± 0.42 ** | 0.71 | 0.57 ± 0.59 * | 0.14 | |
3 | 0.71 ± 0.41 ** | 0.71 ± 0.41 ** | 0.57 | 0.29 ± 0.36 * | 0.43 | |
4 | 0.86 ± 0.09 ** | 0.43 ± 0.36 *.** | 0.71 | 0.14 ± 0.17 * | 0.71 | |
5 | 1.14 ± 0.06 ** | 0.29 ± 0.27 * | 0.71 | 0.43 ± 0.42 * | 0.14 | |
Σ 1–5 | 5.14 ± 0.04 ** | 3.29 ± 0.27 ** | 3.86 | 2.14 ± 0.07 * | 2.29 | |
Total time of staying in the illuminated branches of the maze, s | 1 | 35.14 ± 0.02 ** | 34.71 ± 0.11 ** | 32.71 | 14.71 ± 0.11 * | 7.14 |
2 | 26.57 ± 0.20 ** | 36.29 ± 0.04 ** | 22.71 | 15 ± 0.60 * | 6 | |
3 | 27.43 ± 0.01 ** | 20.14 ± 0.11 ** | 25.86 | 7.14 ± 0.08 * | 3.86 | |
4 | 25.14 ± 0.07 ** | 19.43 ± 0.13 ** | 27.43 | 9.43 ± 0.24 | 8.86 | |
5 | 24.14 ± 0.11 ** | 18.29 ± 0.17 ** | 24.86 | 10.71 ± 0.11 * | 0.86 | |
Σ 1–5 | 138.43 ± 0.04 ** | 128.86 ± 0.02 ** | 133.57 | 57 ± 0.11 * | 26.71 | |
Total time of staying in the central location, s | 1 | 5.86 ± 0.86 ** | 7.14 ± 0.31 ** | 8.43 | 4.57 ± 1 * | 7.29 |
2 | 9.86 ± 0.15 ** | 5.29 ± 0.07 * | 12.86 | 3.14 ± 0.07 * | 8.43 | |
3 | 8.86 ± 0.73 ** | 6.43 ± 0.34 * | 11.43 | 8.43 ± 0.46 * | 4.29 | |
4 | 10.29 ± 0.12 ** | 7.86 ± 0.61 * | 10.71 | 3.43 ± 0.17 * | 5 | |
5 | 22 ± 0.06 ** | 8.14 ± 0.34 * | 12.43 | 6.71 ± 0.17 * | 4.57 | |
Σ 1–5 | 56.86 ± 0.12 ** | 34.86 ± 0.23 * | 55.86 | 26.29 ± 0.23 * | 29.57 | |
Number of cases of looking down (risk assessment) | 1 | 4.86 ± 0.09 ** | 2.57 ± 0.91 ** | 2.43 | 2.57 ± 1 * | 1.29 |
2 | 3.14 ± 0.40 * | 3.29 ± 0.10 * | 1.71 | 2.14 ± 0.78 * | 0.57 | |
3 | 3.71 ± 0.23 */** | 1.57 ± 0.10 * | 2.14 | 2.14 ± 0.89 * | 0.43 | |
4 | 3.57 ± 0.02 ** | 1.29 ± 0.20 * | 2.86 | 1.43 ± 0.34 * | 0.71 | |
5 | 4.57 ± 0.04 ** | 1.71 ± 0.05 * | 3.57 | 1.43 ± 0.07 * | 0.29 | |
Σ 1–5 | 19.86 ± 0.02 ** | 10.43 ± 0.17 * | 12.71 | 9.71 ± 0.75 * | 3.29 | |
The latent period of the first appearance in the branch of the maze | 0.07 ± 0.34 ** | 0.36 ± 0.28 * | 0.78 | 0.8 ± 0.79 * | 1.52 |
Note: Group I—animals treated with hydroethanolic extract, group II—animals treated with water extract, group III—animals treated with Hypericum tincture, n—number of animals, *—the reliability of deviations in relation to the control group data, **—the reliability of deviations in relation to the reference group data (p ≤ 0.05).