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. 2020 Jun 15;9(6):751. doi: 10.3390/plants9060751

Table 4.

Behavior of animals in conditions of the “Elevated Plus Maze” test.

Indicator Number of Animals Groups
Group I Group II Control Group III Intact Animals
1 2 3 4 5 6 7
Total number of appearances in the dark chamber 1 2 ± 0.24 *,** 1.14 ± 0.36 ** 1.14 1.43 ± 0.42 * 1.71
2 1.71 ± 0.20 ** 1.43 ± 0.10 ** 2.14 0.57 ± 0.04 * 1.71
3 1.43 ± 0.29 * 2.29 ± 0.05 * 0.71 0.86 ± 0.71 * 1.43
4 1.86 ± 0.14 * 1.29 ± 0.28 ** 1.29 0.57 ± 0.41 * 1.86
5 1.57 ± 0.36 * 1.29 ± 0.79 ** 1.29 1.43 ± 1 * 1.14
Σ 1–5 8.57 ± 0.31 ** 7.43 ± 0.20 ** 6.57 4.86 ± 0.29 * 7.86
Total time of staying in the dark branches of the maze, s 1 19 ± 0.01 ** 18.14 ± 0.17 ** 18.86 40.71 ± 0.10 * 45.57
2 23.57 ± 0.09 ** 18.43 ± 0.02 ** 24.43 40.86 ± 0.17 * 45.57
3 23.71 ± 0.02 ** 33.43 ± 0.12 ** 22.71 44.43 ± 0.24 * 51.86
4 23.14 ± 0.02 ** 32.71 ± 0.24 ** 21.86 47.14 ± 0.11 * 46.14
5 13.86 ± 0.02 ** 33.57 ± 0.17 ** 22.71 42.57 ± 0.04 * 54.57
Σ 1–5 103.29 ± 0.02 ** 136.29 ± 0.04 ** 110.57 215.71 ± 0.09 * 243.71
Total number of appearances in the central location 1 2.86 ± 0.24 ** 2.29 ± 0.58 * 2 2 ± 1 * 1.43
2 3.14 ± 0.40 ** 2.57 ± 0.34 ** 2.86 1.86 ± 0.20 * 2.43
3 2.14 ± 0.35 ** 2.29 ± 0.27 ** 2 1.14 ± 0.10 * 1.14
4 3.43 ± 0.07 ** 2 ± 0.60 * 2.14 1.14 ± 0.22 * 2.43
5 2.57 ± 0.23 ** 1.14 ± 0.20 * 2.29 1.72 ± 0.68 * 1
Σ 1–5 14.14 ± 0.12 ** 10.29 ± 0.49 ** 11.29 7.86 ± 0.31 * 8.43
Total number of appearances in the illuminated branches of the maze 1 1.57 ± 0.22 ** 1 ± 0.36 ** 1.14 0.71 ± 0.10 * 0.86
2 0.86 ± 0.46 ** 0.86 ± 0.42 ** 0.71 0.57 ± 0.59 * 0.14
3 0.71 ± 0.41 ** 0.71 ± 0.41 ** 0.57 0.29 ± 0.36 * 0.43
4 0.86 ± 0.09 ** 0.43 ± 0.36 *.** 0.71 0.14 ± 0.17 * 0.71
5 1.14 ± 0.06 ** 0.29 ± 0.27 * 0.71 0.43 ± 0.42 * 0.14
Σ 1–5 5.14 ± 0.04 ** 3.29 ± 0.27 ** 3.86 2.14 ± 0.07 * 2.29
Total time of staying in the illuminated branches of the maze, s 1 35.14 ± 0.02 ** 34.71 ± 0.11 ** 32.71 14.71 ± 0.11 * 7.14
2 26.57 ± 0.20 ** 36.29 ± 0.04 ** 22.71 15 ± 0.60 * 6
3 27.43 ± 0.01 ** 20.14 ± 0.11 ** 25.86 7.14 ± 0.08 * 3.86
4 25.14 ± 0.07 ** 19.43 ± 0.13 ** 27.43 9.43 ± 0.24 8.86
5 24.14 ± 0.11 ** 18.29 ± 0.17 ** 24.86 10.71 ± 0.11 * 0.86
Σ 1–5 138.43 ± 0.04 ** 128.86 ± 0.02 ** 133.57 57 ± 0.11 * 26.71
Total time of staying in the central location, s 1 5.86 ± 0.86 ** 7.14 ± 0.31 ** 8.43 4.57 ± 1 * 7.29
2 9.86 ± 0.15 ** 5.29 ± 0.07 * 12.86 3.14 ± 0.07 * 8.43
3 8.86 ± 0.73 ** 6.43 ± 0.34 * 11.43 8.43 ± 0.46 * 4.29
4 10.29 ± 0.12 ** 7.86 ± 0.61 * 10.71 3.43 ± 0.17 * 5
5 22 ± 0.06 ** 8.14 ± 0.34 * 12.43 6.71 ± 0.17 * 4.57
Σ 1–5 56.86 ± 0.12 ** 34.86 ± 0.23 * 55.86 26.29 ± 0.23 * 29.57
Number of cases of looking down (risk assessment) 1 4.86 ± 0.09 ** 2.57 ± 0.91 ** 2.43 2.57 ± 1 * 1.29
2 3.14 ± 0.40 * 3.29 ± 0.10 * 1.71 2.14 ± 0.78 * 0.57
3 3.71 ± 0.23 */** 1.57 ± 0.10 * 2.14 2.14 ± 0.89 * 0.43
4 3.57 ± 0.02 ** 1.29 ± 0.20 * 2.86 1.43 ± 0.34 * 0.71
5 4.57 ± 0.04 ** 1.71 ± 0.05 * 3.57 1.43 ± 0.07 * 0.29
Σ 1–5 19.86 ± 0.02 ** 10.43 ± 0.17 * 12.71 9.71 ± 0.75 * 3.29
The latent period of the first appearance in the branch of the maze 0.07 ± 0.34 ** 0.36 ± 0.28 * 0.78 0.8 ± 0.79 * 1.52

Note: Group I—animals treated with hydroethanolic extract, group II—animals treated with water extract, group III—animals treated with Hypericum tincture, n—number of animals, *—the reliability of deviations in relation to the control group data, **—the reliability of deviations in relation to the reference group data (p ≤ 0.05).