Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Substrate scope with standard reaction conditions: alkyne (0.2 mmol), p-TolI (20 mol %), Selectfluor® (1.5 equiv), H2O (1.0 equiv), CHCl3 (0.5 mL), amine/HF 1:7.5 (0.5 mL), ambient temperature, 24 h. Yields refer to isolated products while 19F NMR yields are given in parentheses (determined by 19F NMR analysis of the crude reaction mixture using ethyl fluoroacetate as internal standard). See Supporting Information File 1 for the exact calculation of the amine/HF mixtures.
