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(A) Inhibitory assay for hrGALNS incubated with fluorogenic substrate 4MUGPS with or without BC. The results are reported as the percentage of the enzyme activity relative to the control group. (B) Effect of BC on the production of hrGALNS in HEK293 cells. Cells were transfected with plasmid pCXN-GALNS and treated with different concentrations of BC. (ANOVA Holm-Šidák test * p < 0.01, ** p < 0.001, *** p < 0.0001, n = 3.)
