Table 2. Affinity Energies for Substrates against GALNS Crystal Structure with FGly79 or Cys79.

	Affinity energy (kcal mol–1)
Substrate	GALNS–Cys79	GALNS–FGly79
KS	–7.7	–8.3
C6S	–6.3	–6.7
G6S	–5.2	–5.7
4MUGPS	–5.4	–5.7