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. 2020 Apr 6;103(1):55–63. doi: 10.4269/ajtmh.19-0818

Table 4.

Summary of antibody isotype positivity cutoff titer in selected studies

Country IgG positivity cutoff titer Studies (n) References
≥ 1:40 1:64 ≥ 1:64 ≥ 1:80 ≥ 1:128 > 1:128 ≥ 1:960 > 1:960
Brazil 1 1 45
China 1 1 77
Cyprus 1 1 78
France 1 1 40
Germany 1 1 79
Greece 1 1 1 3 48,80,81
Nepal 1 1 82
New Zealand 1 1 39
Spain 1 2 1 4 14,37,58,61
Sri Lanka 1 1 83
Tunisia 1 1 2 19,69
United States 1 2 1 4 84,70,71,85
Total (n) 2 2 4 2 5 2 2 2 21
Country IgM positivity cutoff titer Studies (n) References
≥ 1:32 ≥ 1:40 ≥ 1:64 > 1:64 ≥ 1:80 > 1:80 ≥ 1:400 > 1:400
Brazil 1 1 45
China 1 1 79
Colombia 1 1 88
Cyprus 1 1 78
France 1 1 40
Greece 1 1 2 4 48,80,81,87
Indonesia 1 1 88
Israel 1 1 28
Lao PDR 1 1 2 50,75
Nepal 1 1 16
Spain 1 1 56
Sri Lanka 1 1 83
Taiwan 5 1 6 63,89,90,91,92,93
Tanzania 1 1 65
Tunisia 3 1 4 19,68,67,69
United States 1 1 94
Zambia 1 1 73
Total (n) 4 2 8 3 5 1 4 2 29
Country Whole antibody positivity cutoff titer Studies (n) References
≥ 1:32 ≥ 1:50 > 1:50 ≥ 1:64 ≥ 1:100 ≥ 1:200 ≥ 1:400 ≥ 1:800
Israel 1 1 74
Lao PDR 1 1 76
Malaysia 1 1 53
Tanzania 1 1 66
Thailand 1 1 2 95
Tunisia 1 1 67
Zambia 1 1 73
Total (n) 1 1 1 1 1 1 1 1 8

* If the positivity cutoff titer was only seen once, then it was not included on the table.

† Studies performed on travelers were excluded.