Table 2.

Binding energy scores obtained for the proteins IL-1β and NF-κB with Piperine, PPL and analogues.

Molecules	Energy Score kcal/mol (IL-1B)	Energy Score kcal/mol (NF-KB)
Piperine	−6.08	−6.08
3a	−6.04	−6.53
3b	−7.44	−6.24
3c	−6.25	−6.07
4a	−7.18	−6.64
4c	−7.22	−6.4
PPL	−5.83	−5.36
9a	−5.38	−5.85
10	−6.19	−5.72
9b	−5.62	−5.87