Table 5.
Skin reaction scores of (1) the initial test (one rabbit) and (2) the confirmatory test (two rabbits) upon removal of patch, where time indicates the time after the removal of a patch and 0 h indicates the immediate observation upon removal of a patch.
| (1) Initial Response | |||||||
| Time (h) | CHEN | CDEN | |||||
| Corrosion | Irritation | Corrosion | Irritation | ||||
| Erythema | Edema | Erythema | Edema | ||||
| 0 | No corrosive lesion observed | 1 | 1 | No corrosive lesion observed | 1 | 0 | |
| 1 | No corrosive lesion observed | 1 | 0 | No corrosive lesion observed | 1 | 0 | |
| 24 | Brownish line lesion seen (5 mm length) | 1 | 0 | No corrosive lesion observed | 2 | 0 | |
| 48 | - | - | - | Slight erosion on the skin | 1 | 0 | |
| (2) Confirmatory response | |||||||
| Time (h) | Rabbit No. | CHEN | CDEN | ||||
| Corrosion | Irritation | Corrosion | Irritation | ||||
| Erythema | Edema | Erythema | Edema | ||||
| 0 | 1 | No corrosive lesion observed | 1 | 1 | No corrosive lesion observed | 0 | 0 |
| 2 | No corrosive lesion observed | 0 | 0 | No corrosive lesion observed | 1 | 1 | |
| 1 | 1 | No corrosive lesion observed | 1 | 0 | No corrosive lesion observed | 0 | 0 |
| 2 | No corrosive lesion observed | 1 | 1 | No corrosive lesion observed | 1 | 0 | |