Table 6.
Glomerular filtration rate (eGFR; mL/min/1.73 m2) in patients with and without arterial hypertension.
| Time Point | LCPT | Standard-Release Tac | ||||
|---|---|---|---|---|---|---|
| Arterial Hypertension (n = 36) |
Normal Blood Pressure (n = 25) |
p-Value | Arterial Hypertension (n = 37) |
Normal Blood Pressure (n = 23) |
p-Value | |
| t0 | 59.3 ± 20.7 | 74.3 ± 18.7 | 0.006 | 66.8 ± 21.0 | 76.6 ± 14.5 | 0.056 |
| t3 | 63.4 ± 22.4 | 73.1 ± 19.2 | 0.111 | 64.6 ± 22.4 | 74.2 ± 16.7 | 0.121 |
| t6 | 62.6 ± 20.1 | 74.2 ± 18.5 | 0.038 | 65.5 ± 20.4 | 77.6 ± 12.7 | 0.015 |
| t9 | 65.1 ± 19.9 | 74.7 ± 20.7 | 0.120 | 63.2 ± 21.8 | 70.4 ± 16.3 | 0.222 |
| t12 | 66.7 ± 17.0 | 76.9 ± 18.3 | 0.042 | 61.2 ± 22.4 | 74.5 ± 15.6 | 0.015 |
LCPT, once-daily MeltDose® tacrolimus; Tac, tacrolimus; t0 to t12, time points (months). eGFR values shown as mean ± standard deviation. p-values from t-test.