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. 2020 Jun 17;9(6):1900. doi: 10.3390/jcm9061900

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The EC risk stratification system according to the ESMO-ESGO-ESTRO (European Society for Medical Oncology-European Society of Gynaecological Oncology-European SocieTy for radiotherapy & Oncology) consensus [13] and its associated primary and adjuvant treatment. Clinical, molecular and pathological characteristics used to predict EC treatment and decision tree showing the clinical and pathological features used for the final definition of EC treatment. IHQ: immunohistochemistry; Transvaginal US: transvaginal ultrasonography; CT: computed tomography; MRI: magnetic resonance imaging; PET-CT: positron emission tomography; EEC: Endometrioid endometrial cancer; NEEC: non-endometrioid endometrial cancer; LVSI: lymphovascular space invasion. The information is scaled down to provide a result on the associated risk, primary and adjuvant treatments, and prognosis.