Table 1.
Baseline characteristics of the study population (n = 603).
| Variables | n (%) or Median [IQR] |
|---|---|
| Age (year) | 82 [77–86] |
| Sex (female) | 323 (54) |
| Frailty phenotype (yes) | 352 (58) |
| Cancer site | |
| Colorectal | 109 (18) |
| Breast | 105 (17) |
| Lung | 92 (15) |
| Liver | 85 (14) |
| Digestive tract other than colorectal a | 79 (13) |
| Genito-urinary tract | 40 (7) |
| Haematological malignancies | 34 (6) |
| Skin with melanoma | 16 (2.5) |
| Prostatic | 16 (2.5) |
| Others b | 27 (5) |
| Cancer extension | |
| Local | 104 (17) |
| Locally advanced | 228 (38) |
| Metastatic | 271 (45) |
| Supportive care only (yes) | 124 (20.5) |
| Comorbidities (CIRS(G)): | |
| Total >14 | 269 (45) |
| Dependence | |
| ADL £ 5/6 | 204 (34) |
| IADL £ 3/4 | 386 (64) |
| Nutrition | |
| BMI < 21 kg/m2 | 84 (14) |
| Serum albumin level < 35 g/L | 221 (37) |
| Serum CRP ≥ 10 mg/L | 267 (44) |
| Mobility | |
| SPPB < 9/12 | 314 (52) |
| One-leg stance balance < 5 s | 448 (74) |
| Mood | |
| Mini-GDS ≥ 1/4 | 261 (44) |
| Missing data | 6 (1) |
| Cognition | |
| MMSE < 24/30 | 217 (51) |
| Missing data | 174 (29) |
a: pancreas (n = 28), gastric (n = 20), bile-duct (n = 15), oesophagus (n = 9), gastrointestinal stroma tumour (n = 4), anal (n = 3); b: unknown primary site (n = 10), mesothelioma (n = 8), sarcoma (n = 5), head and neck (n = 3), thymoma (n = 1). ADL: activities of daily living; BMI: body mass index; CIRS(G): Cumulative Illness Rating Scale for Geriatrics; CRP: C-reactive protein; ECOG-PS: Eastern Cooperative Oncology Group performance status; GS: gait speed; IADL: instrumental activities of daily living; Mini-GDS: Mini-Geriatric Depression Scale; MMSE: Mini-Mental State Examination; SPPB: short physical performance battery.