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False negative (per vessel) cCTA example (CAC = 2839): Right coronary artery (RCA) with heavy calcifications and excellent contrast opacification (approx. 600 HU) on cCTA with multiplanar reconstruction (a) and volume rendered technique (b) and invasive coronary angiography depicting a ≥ 50% stenosis in the distal RCA (segment 3) (arrows) (c,d), which is masked on cCTA. CAC = coronary artery calcium score.
